Family: Picornaviridae

Genus: Rohelivirus


Distinguishing features

The genus is distinguished on the basis of genetic characters. 



No details are available on the morphology of virions. 

Nucleic acid

Genome (Wu et al., 2018): c. 7,780–7,823 nt (5′-UTR: up to 1,239 nt; ORF: 6,489–6,510 nt; 3'-UTR: 71–89 nt). The location of the cre has not been identified. 

Genome organization and replication

Genome layout:


The deduced polyprotein is of 2,163–2,170 amino acids. There is no L protein. 1A is very short (16 amino acids). The function of 2A is unknown. 


No virus has been isolated. Viral RNA was detected in pharyngeal and anal swabs of northern three-toed jerboas (Dipus sagitta) and Chinese white-bellied rats (Niviventer confucianus) captured in the Inner Mongolia, Shaanxi and Tibet provinces of China. Three genetic types, rohelivirus A1, A2 and A3, are distinguished by means of phylogenetic clustering. 

Derivation of names

Rohelivirus: derived from Rodentia (order rodents, host) and hepato-like virus

Species demarcation criteria

There is only a single species in the genus.