Family: Picornaviridae
Genus: Crohivirus
Distinguishing features
The genus is distinguished on the basis of genetic characters.
Virion
Morphology
No details are available on the morphology of virions.
Nucleic acid
Genome (Sasaki et al., 2015, Yinda et al., 2017): 7,085–7,321 nt (5′-UTR: c. 517 nt; ORF: 6,510–6,519 nt; 3′-UTR: >58–294 nt). The location of the cre has not been identified.
Genome organization and replication
Genome layout:
VPg+5′-UTRIRES-[1AB-1C-1D-2A1npgp/2A2H-box/NC-2B-2C/3A-3B-3C-3D]-3′-UTR-poly(A)
The deduced polyprotein is c. 2,170 amino acids. There is no L protein. The 1AB protein remains uncleaved.
Biology
No virus has been isolated. Viral RNA was detected in faeces and intestinal contents, respectively, of wild shrews in Zambia and fruit bats (Eidolon helvum) in Cameroon.
Derivation of names
Crohivirus: from Crocidura hirta (the lesser red musk shrew from which the first strain was isolated)
Species demarcation criteria
Members of a species of the genus Crohivirus:
- share a common genome organization
- are less than 55% divergent in polyprotein aa sequence
- are less than 60% divergent in P1 aa sequence
- are less than 50% divergent in 2C + 3CD aa sequence