The genus is distinguished on the basis of genetic characters.
No details are available on the morphology of virions.
Genome (Wu et al., 2016): c. 7,050 nt (5′-UTR: >337 nt; ORF: 6,501–6,624 nt; 3′-UTR: 87–98 nt). The location of the cre has not been identified.
Genome organization and replication
The deduced polyprotein is of 2,167–2,208 amino acids. There is no L protein. The 2A protein has been proposed to be a chymotrypsin-like protease.
No virus has been isolated. Viral RNA was detected in pharyngeal and anal swabs of bats (Rhinolophus affinis, R. ferrumequinum, R. lepidus, Nyctalus velutinus).
Derivation of names
Diresapivirus: derived from acronym "distant relatives of rabo-, entero-, sapelo-, anativiruses" and picornavirus
Species demarcation criteria
Members of a species of the genus Diresapivirus:
- are less than 30% divergent in polyprotein aa sequence
- are less than 40% divergent in P1 aa sequence
- are less than 35% divergent in 2C+3CD aa sequence
- share a common genome organization
Related, unclassified viruses
diresapivirus A1 [BtRlep-PicoV/FJ2012]
diresapivirus A1 [BtRa-PicoV/JS2013]