Family: Picornaviridae

Genus: Diresapivirus


Distinguishing features

The genus is distinguished on the basis of genetic characters. 



No details are available on the morphology of virions. 

Nucleic acid

Genome (Wu et al., 2016): c. 7,050 nt (5′-UTR: >337 nt; ORF: 6,501–6,624 nt; 3′-UTR: 87–98 nt). The location of the cre has not been identified. 

Genome organization and replication

Genome layout:


The deduced polyprotein is of 2,167–2,208 amino acids. There is no L protein. The 2A protein has been proposed to be a chymotrypsin-like protease. 


No virus has been isolated. Viral RNA was detected in pharyngeal and anal swabs of bats (Rhinolophus affinis, R. ferrumequinum, R. lepidus, Nyctalus velutinus). 

Derivation of names

Diresapivirus: derived from acronym "distant relatives of rabo-, entero-, sapelo-, anativiruses" and picornavirus

Species demarcation criteria

Members of a species of the genus Diresapivirus:

  • are less than 30% divergent in polyprotein aa sequence
  • are less than 40% divergent in P1 aa sequence
  • are less than 35% divergent in 2C+3CD aa sequence
  • share a common genome organization

Related, unclassified viruses

Virus name

Accession number

Virus abbreviation

diresapivirus A1 [BtRlep-PicoV/FJ2012]



diresapivirus A1 [BtRa-PicoV/JS2013]



Virus names and virus abbreviations are not official ICTV designations. 
* partial genome