Ampullaviridae Table of Contents

Adenoviridae Table of Contents

Flaviviridae Table of Contents

Family: Flaviviridae

Authors:

Rebecca Rico-Hesse, Tatjana Avsic-Zupanc, Bradley Blitvich, Jens Bukh, Van-Mai Cao-Lormeau, Allison Imrie, Amit Kapoor, Laura D Kramer, Brett D Lindenbach, Peter Simmonds, Donald B. Smith and Pedro Fernando da Costa Vasconcelos

Family: Flaviviridae

Genus: Pestivirus

Family: Flaviviridae

Genus: Pegivirus

Distinguishing features

Pegiviruses have been detected in a variety of mammalian hosts, with transmission of human pegiviruses occurring by sexual, parenteral and maternal routes. Invertebrate vectors have not been discovered. 

Family: Flaviviridae

Genus: Hepacivirus

Family: Flaviviridae

Genus: Orthoflavivirus

Distinguishing features

The 5′-end of the genome possesses a type I cap (m⁷GpppAmp) not seen in viruses of the other genera. Most orthoflaviviruses are transmitted to vertebrate hosts by arthropod vectors, mosquitoes or ticks, in which they replicate actively. Some orthoflaviviruses transmit between rodents or bats without known arthropod vectors. 

Frederick A. Murphy
University of Texas Medical Branch
Department of Pathology, Route 0609
301 University Boulevard

A paper that discusses issues related to the taxonomic classification of viruses discovered through metagenomic sequencing has been published in Current Opinion in Virology: