Family: Chuviridae

Genus: Doliuvirus


Distinguishing features

Doliuviruses are primarily distinguished from viruses of other genera in the family based on nucleic acid sequence and organization differences (Di Paola et al., 2022). Members of the genus Doliuvirus have L protein sequences that are >31% identical to each other.

Genome organization and replication

Doliuviruses have bisegmented linear genomes of about 11.5 kb (S1: about 6.8 kb; S2: about 4.7 kb) with four ORFs encoding a glycoprotein (GP) , a large (L) protein with an RNA-directed RNA polymerase (RdRP) domain, and proteins of unknown function. The replication cycle of doliuviruses remains to be elucidated.


The only classified doliuvirus, Mos8Chu0 chuvirus (MoCV), has been associated with dipteran insects, specifically mosquitoes (culicid Culiseta minnesotae Barr, 1957), in the USA (unpublished). Unclassified doliuviruses have been associated with mosquitoes in Brazil.

Species demarcation criteria

New doliuvirus species should be established when the amino-acid identities of their complete L protein sequence are <90% compared to other viruses in the genus (Di Paola et al., 2022).

Virus nameAccession numberVirus abbreviationReference
Croada virusMF344588* (Lara Pinto et al., 2017)
Cumbaru virusMF344596* (Lara Pinto et al., 2017)
Guato virusKT966484* (Pauvolid-Corrêa et al., 2016)
Kaiowa virusKT966481* (Pauvolid-Corrêa et al., 2016)
midge associated chuvirus M1C6LR701645* (Modha et al., 2019)
midge associated chuvirus M1C7LR701646* (Modha et al., 2019)
midge associated chuvirus M1C8LR701647* (Modha et al., 2019)
Uru chuvirusMK780200* (Maia et al., 2019)

Virus names and virus abbreviations are not official ICTV designations.

* Incomplete genome