Genus

Genus: Metapneumovirus

Family: Pneumoviridae

Genus: Metapneumovirus

 

Distinguishing features

Members of the genus Metapneumovirus  possess 8 genes. They lack the two promoter proximal NS1 and NS2 genes found in the members of the genus Orthopneumovirus. The gene order is N-P-M-F-M2-SH-G-L. Alignment of the L proteins of the metapneumoviruses shows a moderate level of conservation between the human and avian viruses. Their genome length is smaller than that of the members of the other genus. 

Genus

Genus: Orthopneumovirus

Family: Pneumoviridae

Genus: Orthopneumovirus

 

Distinguishing features

Members of the genus Orthopneumovirus possess 10 genes including two NS1 and NS2 which are promoter proximal (i.e. before) the N gene. The gene order is NS1-NS2-N-P-M-SH-G-F-M2-L. Alignments of the L proteins show moderate conservation of the sequences between the human, murine, bovine and ovine viruses. Their genome length is larger than that of the members of the other genus.