Subfamily: Orthocoronavirinae

Family: Coronaviridae

Subfamily: Orthocoronavirinae

Distinguishing features

The subfamily Orthocoronavirinae was established for four genera based upon DEmARC analysis of the nidovirus-wide conserved 3CLpro, NiRAN, RdRP, ZBD and HEL1 domains. This subfamily consists of a large clade with 4 distinct branches in phylogenetic trees (Figure 5.Coronaviridae), these corresponding to the genera Alphacoronavirus, Betacoronavirus, Deltacoronavirus and Gammacoronavirus. Members of this subfamily can infect a wide range of mammals and birds.

Genus demarcation criteria

Details correspond to the family descriptions.

International Committee on Taxonomy of Viruses

Unless otherwise noted, this work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License

Support is provided by the National Institute of Allergy and Infectious Diseases, U.S. National Institutes of Health, Award U24AI162625