REMAINING PROVISIONALLY ASSIGNED HCV SUBTYPES (November 2014)
Accession number(s)2 | |||||
---|---|---|---|---|---|
Genotype/Subtype | Isolate1 | Core/E1 | NS5B | Reference(s) | |
Genotype 1 | |||||
1f | FR2 | L38350 | L38371 | (Stuyver et al., 1995) | |
Genotype 2 | |||||
2g | MED017 | n.a. | X93323 | (Ruggieri et al., 1996) | |
2h | MED007 | n.a. | X93327 | (Ruggieri et al., 1996) | |
2n | NL50 | L39309 | L44602 | (Stuyver et al., 1995) | |
2o | FR4 | L38333 | L38373 | (Stuyver et al., 1995) | |
2p | NL33 | L39300 | L44601 | (Stuyver et al., 1995) | |
2s | C1966 | JQ924942/ HM777447 | HM777332 | (Sulbarán et al., 2010) | |
Genotype 3 | |||||
3c | NE048 | D16612 | D14198/D16613 | (Tokita et al., 1994) | |
3f | NE125, PK64 | D16614 , n.a. | D14203/D16615, L78842 | (Tokita et al., 1994)(Stuyver et al., 1996) | |
Genotype 4 | |||||
4e | CAM600, GB809 | L29589, L29629 | L29590, L29626 | (Stuyver et al., 1994) | |
4h | GB438, FrSSD35 | L29610, n.a. | L29611, AJ291249 | (Stuyver et al., 1994)(Morice et al., 2001) | |
4i | CAR4/1205 | L36439 | L36437 | (Fretz et al., 1995) | |
4j | CAR1/501 | n.a. | L36438 | (Fretz et al., 1995) |
1 Listing of up to two examples of each provisionally assigned HCV subtype prioritized according to (i) completeness (availability of complete or near complete core/E1 and NS5B sequences), (ii) publication date, (iii) GenBank submission date
2Accession numbers of sequences from the core/E1 and NS5B regions. “n.a.”: not available; “/”: denotes that the core/E1 or NS5B sequences are available from two different accession numbers
References
Fretz, C., Jeannel, D., Stuyver, L., Hervé, V., Lunel, F., Boudifa, A., Mathiot, C., De Thé, G. & Fournel, J. J. (1995). HCV infection in a rural population of the Central African Republic (CAR): evidence for three additional subtypes of genotype 4. J Med Virol 47, 435–437.
Morice, Y., Roulot, D., Grando, V., Stirnemann, J., Gault, E., Jeantils, V., Bentata, M., Jarrousse, B., Lortholary, O. & other authors. (2001). Phylogenetic analyses confirm the high prevalence of hepatitis C virus (HCV) type 4 in the Seine-Saint-Denis district (France) and indicate seven different HCV-4 subtypes linked to two different epidemiological patterns. J Gen Virol 82, 1001–1012.
Ruggieri, A., Argentini, C., Kouruma, F., Chionne, P., D’Ugo, E., Spada, E., Dettori, S., Sabbatani, S. & Rapicetta, M. (1996). Heterogeneity of hepatitis C virus genotype 2 variants in West Central Africa (Guinea Conakry). J Gen Virol 77, 2073–2076.
Stuyver, L., Van Arnhem, W., Wyseur, A., Hernandez, F., Delaporte, E. & Maertens, G. (1994). Classification of hepatitis C viruses based on phylogenetic analysis of the envelope 1 and nonstructural 5B regions and identification of five additional subtypes. Proc Natl Acad Sci U S A 91, 10134–10138.
Stuyver, L., Wyseur, A., Van Arnhem, W., Lunel, F., Laurent-Puig, P., Pawlotsky, J. M., Kleter, B., Bassit, L., Nkengasong, J. & Van Doorn, L. J. (1995). Hepatitis C virus genotyping by means of 5’-UR/core line probe assays and molecular analysis of untypeable samples. Virus Res 38, 137–157.
Stuyver, L., Wyseur, A., Van Arnhem, W., Hernandez, F. & Maertens, G. (1996). Second-generation line probe assay for hepatitis C virus genotyping. J Clin Microbiol 34, 2259–2266.
Sulbarán, M. Z., Di Lello, F. A., Sulbarán, Y., Cosson, C., Loureiro, C. L., Rangel, H. R., Cantaloube, J. F., Campos, R. H., Moratorio, G. & other authors. (2010). Genetic History of Hepatitis C Virus in Venezuela: High Diversity and Long Time of Evolution of HCV Genotype 2. PLoS One 5, E14315 (S. M. Bowyer, Ed.). Public Library of Science.
Tokita, H., Shrestha, S. M., Okamoto, H., Sakamoto, M., Horikita, M., Iizuka, H., Shrestha, S., Miyakawa, Y. & Mayumi, M. (1994). Hepatitis C virus variants from Nepal with novel genotypes and their classification into the third major group. J Gen Virol 75, 931–936.